In 1995, after eight seasons, the series came to an end.
Stamos has since maintained close relationships with co-stars Bob Saget, Dave Coulier, Lori Loughlin, Jodie Sweetin, Mary-Kate and Ashley Olsen, Andrea Barber, and Candace Cameron Bure.
He played one of the show's protagonists, Jesse, who lives with his brother in-law, whose deceased wife was Jesse's older sister.
Danny's best friend, Joey, also lives in the house with them. Jesse is known to be the "bad boy" at first, until he falls in love with and marries Rebecca Donaldson and has twin boys, Nicky and Alex.
Stamos has appeared in numerous made-for-television films, stage productions, television series and commercials.
Stamos began his acting career with the role of Blackie Parrish on the soap opera General Hospital in late January 1982, for which he was nominated for a Daytime Emmy Award in 1984.
That April, he went on to the lead role in the short-lived CBS sitcom Dreams, in which he played an aspiring musician in a band of the same name.
He is known for his work in television, especially in his starring role as Jesse Katsopolis on the ABC sitcom Full House.Since the show's finale in 1995, Stamos has appeared in numerous TV films and series.From September 2015 to 2016, Stamos starred as the lead character in the Fox sitcom Grandfathered.As of 2015, he has been executive producer of the Netflix series Fuller House, as well as making occasional appearances reprising his role of Jesse Katsopolis.Since 2005, he has been the national spokesperson for Project Cuddle.